Stable and reliable performance
Filling Accuracy: ≤ ±1%
Configurable on-line monitoring system
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Plastic Bottle BFS(Blow Fill Seal)Machine LVP (large volume parenteral) Production Line
AIPAK Engineering plastic bottle BFS machine LVP production line is an advanced technology that integrates molding, filling and sealing under complete control, which enables liquid to be packaged in polypropylene/high-density & low-density polyethylene plastic bottle, and the whole production process automatically completes extruding plastic particles into plastic preform at high temperatures,then the preform is blown into a container by sterilized and filtered air,flling liquid that have been sterilized and filtered,tight sealing of containers after filling in a controlled environment (aseptic environment).
The plastic bottle BFS machine LVP production line can effectively reduce the pollution of human operation, environmental, matierial and so on. It meets the requirements of aseptic production process which widely apply to various areas of plastic bottle sterile liquid preparation.
BFS machine LVP example:
Plastic Bottle BFS(Blow Fill Seal)Machine LVP (large volume parenteral) Production Line Features:
1.The design, MOC, manufacturing, assembly and debugging of the BFS machine meet the requirements of the new GMP or FDA standards for drug production.
2.Advanced equipment, unique and reasonable structure, stable and reliable performance.
3.Applicable Specification: 0.2ml-1000ml plastic bottle (as per user's requirements).
4.Production Capacity: 1000-18000BPH for Pharmaceutical Automatic Aseptic Plastic Bottle BFS Blowing Filling Sealing for IV Injection Solution Machine.
5.The number of bottles made each time: 1-30 bottles/mould, can be selected based on production capacity.
6.Filling Accuracy: ≤ ±1% (according to drug characteristics) for Pharmaceutical Small Capacity BFS Aseptic IV Infusion Filling Machine.
7.The BFS machine is integrated with bottle-making, filling and sealing, with compact structure and occupies small area, which reduces clean workshop area and saves energy consumption of air conditioning unit, as well as investment and use cost.
8.The plastic particles are plasticized by a low speed long screw extruder driven by a specially designed servo motor, which can effectively reduce thermal stress of the material and accurately control the size of bottle preforms.
9.Each working cycle of the equipment can be compared and controlled automatically, with real-time feedback.
10.Stainless steel 304 hopper at extrusion station of the equipment is equipped with a level switch and linked with feeding device; when the material level is getting lowered, the alarm information of "lack of material" will be displayed on man-machine interface.
11.High production efficiency, stable product performance, simple and reliable operation and beautiful appearance.
12.For large capacity products, the container thickness is controlled at 100 points by an advanced thickness controller, and the precision servo motor controls the gap between mold core and mold cup.
13.The filling system is accurately calculated by time pressure method with high filling precision, which can meet filling range of 0.2ml-2000ml to ensure production speed.
14.The equipment has black and white sections, the moving parts are isolated in non-clean are(black area), and only the basic components and operations are kept in clean area(white area), which reduces the area of clean room and the number of particles in clean room.
15.Automatic in-place cleaning / in-place sterilization function (CIP/SIP) can be realized.
16.Configurable on-line monitoring system for dust particles and plankton bacteria.
17.In the process of bottle transfer, the inner surface of interface is not in contact with parts, which eliminates the produce of visible foreign matter.
18.To realize fully automatic control and monitor of production process, high precision color touch screen operation monitoring, PLC automatic control, automatic protection, host frequency conversion speed regulation and other control technology are used.
19.The products can be customized according to actual demand of customers.
Plastic Bottle BFS(Blow Fill Seal)Machine LVP (large volume parenteral) Production Line Technical Specification:
| Product model | HQS -20-B | HQS -30-A | HQS20 -30-B | HQD-6 | HQD-8 | HQS -20-2 | HQS -12-2 | HQS -16-2 | HQS -30-2A | HQS -30-2B | HQD -6-2 | HQD -8-2 |
| mould | 1 | 2 | ||||||||||
| Tubular embryo number | 4 | 3 | 6 | 8 | 4 | 3 | 6 | 8 | ||||
| Number of single blastocyst | 4 | 5*2 | 10 | 1 | 5 | 3 | 4 | 5*2 | 10 | 1 | ||
| Total number of cavities | 16 | 30 | 30 | 6 | 8 | 40 | 24 | 32 | 60 | 60 | 12 | 16 |
| Filling range (ml) | 5-30 | 0.2-0.8 | 1-2 | 500-1000 | 50- 500 | 5-20 | 10-30 | 5-30 | 0.2-0.8 | 1-2 | 500-1000 | 50-500 |
| Production capacity (bottles/hour) | 5400 | 9000 | 9000 | 100-1100 | 1600-1800 | 12000 | 7200 | 9600 | 18000 | 18000 | 1800-2000 | 3200-3600 |
| Overall dimensions (mm) | 5500x2800(6000)x 3000 | 6000x 3500x 3000 | 6000x5000(10000)x3000 | 6000x 6000x 3000 | ||||||||
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