Top 20 Antibiotic Manufacturers In USA

The emergence of antibiotics has saved countless lives and opened the golden age of medicine. The correct term for antibiotics is antibiotics. Antibiotics are divided into two categories: antibiotics and synthetic antibiotics, which refer to a class of drugs that have inhibitory or bactericidal effects on bacteria.

American biotechnology has a place in the world. Do you know which antibiotic manufacturers are in the United States? Next, we will introduce you to the top 20 antibiotic manufacturers in the USA.

Rank Manufacturers Location
1 Pfizer New York
2 Merck & Co. New Jersey
3 Johnson & Johnson California
4 Gilead Sciences California
5 Abbott Laboratories California
6 Eli Lilly & Co. New Jersey
7 Bristol Myers Squibb Company New Jersey
8 Otsuka America Pharmaceutical, Inc. California
9 Regeneron Pharmaceuticals Inc New York
10 AbbVie Inc. Illinois
11 Vertex Pharmaceuticals California
12 MannKind Corporation California
13 Novartis New Jersey
14 Xencor Inc. California
15 Sanofi New Jersey
16 Perrigo Company Michigan
17 Theravance Biopharm South San Francisco
18 Incyte Corporation Delaware
19 Venatorx Pennsylvania
20 Acurx Pharmaceuticals New Jersey

logo

Headquarter: New York

Pfizers background:

Pfizer

Pfizer was founded in 1849 and is a leading global biopharmaceutical company. Since its establishment, Pfizer has been committed to providing innovative, safe, and effective drugs and vaccine products to patients worldwide to improve human health and quality of life.

Pfizer’s product portfolio covers a wide range of therapeutic areas, including oncology, vaccines, rare diseases, inflammation and immunology, neuroscience, internal medicine, anti infection, and consumer healthcare. The antibiotics produced by the company include azithromycin, cefoperazone, and sulbactam.

Key Products:

Pfizer

BICILLIN® L-A (penicillin G benzathine)

Zithromax

Zithromax

Recommend Reason

  • Pfizer has a long history of establishment and has a solid foundation in the field of antibiotics.
  • The company supports and expands access to reliable and affordable healthcare services worldwide.
  • Pfizer continues to invest in research and development, promoting the emergence of new technologies and therapies.

Headquarter: New Jersey

Merck & Co.s background:

Merck-&-Co.

Merck & Co., with a history of over 130 years, has always been a well-known name in the global pharmaceutical industry. Merck & Co.’s products cover many fields, including tumor, vaccine, cardiovascular, viral therapy, neuroscience, immunology, diabetes, etc.

In addition to business diversification, Merck & Co.’s R&D pipeline is also very rich, with over 30 projects in the third phase, 11 projects awaiting approval, and more than 80 projects in the second phase. If these projects are commercialized, they should bring new sources of income for Merck.

Key Products:

Ceporex™-180

Ceporex™ 180

Recommend Reason

  • For 130 years, Merck & Co. has always followed our mission of saving and improving lives, committed to enhancing lives.
  • Merck & Co. is fulfilling its commitment to improving healthcare accessibility for patients and the general public.
  • Merck & Co.’s antibiotic products are all proved by FDA and other institutions.

3.Johnson & Johnson

Johnson-&-Johnson-logo

Headquarter: California

Johnson & Johnson’s background:

Johnson-&-Johnson

Founded in 1886, Johnson&Johnson is one of the most comprehensive and widely distributed medical and health product companies in the world, with business covering medical technology and innovative pharmaceuticals.

Johnson&Johnson produces a variety of antibiotics, among which cefdinir exerts its antibacterial effect by interfering with bacterial cell wall synthesis, mainly targeting Gram positive and Gram negative bacteria.

Key Products:

Polysporin-Ointment

Polysporin Ointment

Neosporin

Neosporin

Recommend Reason

  • Johnson&Johnson provides a range of innovative products for healthcare professionals.
  • Johnson&Johnson Innovative Pharmaceuticals embodies the characteristic of “putting patients first”in multiple aspects.
  • The company’s innovative pharmaceuticals have significant advantages in talent development.

4.Gilead Sciences

Gilead-Sciences-logo

Headquarter: California

Gilead Sciencess background:

Gilead-Sciences

Gilead Sciences was founded in 1987 and is located in Foster City, California, USA. It is a research-based biopharmaceutical company.

Currently, Gilead has over 8,900 employees in 35 countries around the world, but Gilead remains focused on patients and science. Gilead Sciences’ treatment fields include AIDS, liver disease, cancer, etc.

Key Products:

Amphotericin-B-Liposomal-Injection

Amphotericin B Liposomal Injection

Recommend Reason

  • The company currently has over 20 marketed products and hundreds of ongoing and planned clinical studies.
  • Gilead Sciences is committed to developing breakthrough therapies to treat serious life-threatening diseases.

5.Abbott Laboratories

Abbott-Laboratories logo

Headquarter: California

Abbott Laboratoriess background:

Abbott-Laboratories

Founded in 1888, Abbott Laboratories is a globally renowned multinational healthcare company, headquartered in Abbotston, Illinois, USA, dedicated to improving global human health through innovative medical products and services.

After a century of development, Abbott Laboratories, along with Roche, Danaher, and Siemens, is known as one of the top four companies in the IVD (in vitro diagnostics) industry. Its products cover the fields of nutrition, pharmaceuticals, medical devices, diagnostic instruments, and reagents.

Key Products:

Alinity-m-SARS-CoV-2-Assay

Alinity m SARS-CoV-2 Assay

Recommend Reason

  • The company has been established for 135 years, with the goal of improving the lives of 3 billion people by 2030.
  • Abbott has 115,000 employees in 160 countries worldwide, with annual sales exceeding $40 billion.
  • Abbott’s business is mainly divided into four parts: established pharmaceutical products, diagnostic products, nutritional products, and medical devices.

6.Eli Lilly & Co.

Eli-Lilly-&-Co.logo

Headquarter: New Jersey

Eli Lilly & Co.s background:

Eli-Lilly-&-Co.

Eli Lilly&Co. was founded in 1876 and has factories in 13 countries worldwide, with insulin production capacity covering 143 countries. Eli Lilly has developed from a small pharmaceutical factory in the 19th century to the world’s largest pharmaceutical company by market value (reaching $743.4 billion in 2024).

Eli Lilly&Co.’s core advantages lie in the technology accumulation in the field of diabetes, the “Me better” R&D strategy and the global market layout. Its future growth points include GLP-1 drugs, Alzheimer’s disease therapies, and nuclear drug innovation.

Key Products:

Trulicity

Trulicity

Humalog

Humalog

Recommend Reason

  • Lily has also made significant breakthroughs in the field of cancer treatment, developing various innovative drugs to help patients prolong their lives and improve their quality of life.
  • Lily has gained widespread respect and recognition not only in the pharmaceutical industry, but also in the entire society.

7.Bristol Myers Squibb

Bristol-Myers-Squibb-Company-logo

Headquarter: New Jersey

Bristol Myers Squibb’s background:

Bristol-Myers-Squibb-Company

Established in 1887, Bristol Myers Squibb Company has become a global leader in the field of biomedicine. The company focuses on two major disease areas: viral hepatitis and immune tumors. Currently, its product development pipeline has extensively involved more than 40 disease areas, including over 50 potential drugs.

Key Products:

Yervoy-Injection

Yervoy Injection

Yervoy-ipilimumab

Yervoy Ipilimumab

Recommend Reason

  • Bristol Myers Squibb has leading products in the fields of oncology, immunology, and cardiovascular diseases
  • The company’s strong R&D and innovation capabilities have placed it in an important position in the global pharmaceutical market.

Headquarter: California

Otsukas background:

Otsuka-America-Pharmaceutical,-Inc.

Otsuka America Pharmaceutical was founded in 1989. In 1990, Otsuka Pharmaceutical continued its internationalization by acquiring a stake in Crystal Geyser Water Company in the United States and establishing a sales partnership with Nestle.

The company focuses on researching, developing, and commercializing novel therapies for acute disease patients who are currently hospitalized or receiving treatment in other acute medical settings.

Key Products:

ABILIFY®

ABILIFY® (aripiprazole)

Recommend Reason

  • Otsuka America Pharmaceuticalhas a development history of over 90 years.
  • The company has established 152 subsidiaries and research institutions in 23 countries and regions worldwide.
  • Otsuka, as a globally renowned pharmaceutical company, possesses strong research and innovation capabilities.

Headquarter: New York

Regenerons background:

Regeneron-Pharmaceuticals-Inc.

Regeneron Pharmaceuticals is an American biopharmaceutical company headquartered in Tarrytown, New York. The company was founded in 1988 by Dr. Leonard Schreif and Dr. George Yudier.

Regeneron Pharmaceuticals focuses on the research, development, production, and sales of biopharmaceutical products to treat a range of serious diseases, including cataracts, cardiovascular disease, leukemia, rheumatoid arthritis, wet age-related macular degeneration, and other conditions.

Key Products:

Dupixent

DUPIXENT

Recommend Reason

  • Regeneron Pharmaceuticals is a biotechnology company engaged in drug discovery, invention, development, manufacturing, and commercialization.
  • Regeneron Pharmaceuticals is a role model in the eyes of the biotech industry, and there is no biotech company that does not want to become a Regeneron Pharmaceuticals.
  • The expansion of Regeneron Pharmaceuticals in the international market also needs to be further strengthened.

Headquarter: Illinois

AbbVie Inc.s background:

AbbVie-Inc.

Abbvie is a global, research-based biopharmaceutical company engaged in the development and sale of advanced therapies to address some of the world’s most complex and severe diseases.

Abbvie’ main products have been approved in the United States, European Union, and Japan for the treatment of certain Gram positive bacteria and bloodstream infections.

Key Products:

EPKINLY

EPKINLY

OnabotulinumtoxinA

OnabotulinumtoxinA

Recommend Reason

  • Abbvie, a globally leading research-oriented biopharmaceutical company, is committed to solving complex and challenging disease problems with its innovative drugs and solutions.
  • Abbvie is a monoclonal antibody drug targeting human growth hormone, mainly used to treat certain types of cancer.
  • The company has branches in multiple countries around the world, with operations in over 170 countries and regions.

Headquarter: California

Vertexs background:

Vertex-Pharmaceuticals

Founded in 1989, Vertex Pharmaceuticals is a global biotechnology company dedicated to discovering, developing, manufacturing, and commercializing small molecule drugs for severe disease patients. The company focuses on developing and commercializing treatments for diseases such as cystic fibrosis.

Key Products:

Kalydeco-150mg

Kalydeco 150mg

Recommend Reason

  • Vertex Pharmaceuticals has rich experience and leading technology in new drug development, and its pipeline layout and technology platform in the new drug development process also have many unique features.
  • Vertex Pharmaceuticals has a complete drug pipeline that covers the entire process from drug discovery, preclinical research to market and marketing.
  • Vertex Pharmaceuticals also has a high level of target layout capability.

12.MannKind Corporation

MannKind-Corporation-logo

Headquarter: California

MannKind Corporations background:

MannKind-Corporation

Mannkind Corporation was registered and established in Delaware, United States on February 14, 1991. Mannbind Corporation is a biopharmaceutical company focusing on the development, research and promotion of therapies and drugs such as diabetes and cancer.

The company’s leading candidate product, AFREZZA inhalation powder, is an ultra fast acting insulin preparation.

Key Products:

Afrezza

Afrezza

Recommend Reason

  • MannKind, founded by Alfred E. Mann, has been on an extraordinary journey since 1991.
  • MannKind is a biopharmaceutical company focusing on the development and promotion of diabetes and tumor drugs.
  • The company focuses on the research and development of antibiotics and has obtained multiple patents.

Headquarter: New Jersey

Novartiss background:

Novartis

Novartis is a company focused on innovative drugs. The company focuses on four core treatment areas with urgent patient needs: cardiovascular, renal and metabolic, oncology, immunology, and neuroscience.

Since its establishment, Novartis has provided high-quality services to over 500 leading enterprises, helping customers expand their business in global markets and achieve remarkable commercial value.

Key Products:

ZOLGENSMA

ZOLGENSMA

AMOXICILLINE

AMOXICILLINE

Recommend Reason

  • The company’s products involves inpharmaceuticals, diagnostics, medical devices, health food, and digital healthcare.
  • Novartis operates in over 150 countries and regions worldwide, with 138,000 full-time employees
  • Novartis is one of the world’s three major pharmaceutical companies.

Headquarter: California

Xencor Inc.s background:

Xencor-Inc.

Xencor, Inc. was founded in California in August 1997 as a clinical stage biopharmaceutical company. The company focuses on discovering and developing engineered antibody therapies to treat cancer and autoimmune disease patients.

Xencor, Inc. utilizes its XmAb technology platform to develop antibody candidate products to help patients treat cancer and immune related diseases.

Key Products:

Amoxicillin

Amoxicillin

Recommend Reason

  • Xencor is a clinical stage biopharmaceutical company.
  • The company has developed multiple antibiotic products that have helped tens of thousands of patients.
  • The company has also developed technology platforms with different functional antibodies, such as bispecific fc.

Headquarter: New Jersey

Sanofis background:

Sanofi

Founded in 1973, Sanofi is a leading global pharmaceutical and healthcare company that focuses on patient needs, researching, developing, and promoting innovative treatment plans. Sanofi’s business scope is very extensive, covering multiple fields such as specialty drugs, generic drugs, vaccines, and health pharmaceuticals.

At present, Sanofi has multiple production and research and development bases in China, and has introduced more than 60 innovative drugs and vaccines. This global layout not only enhances Sanofig’s international competitiveness, but also enables it to better serve patients worldwide.

Key Products:

ORELOX

ORELOX

Recommend Reason

  • As a globally leading pharmaceutical company, Sanofi has always been committed to fulfilling its social responsibility and promoting sustainable development through various means.
  • Sanofi also focuses on employee development and the construction of a culture of social responsibility.
  • Through mergers and acquisitions, technological innovation, and fulfilling social responsibility, Sanofi has consolidated its leading position in the global pharmaceutical industry.

16.Perrigo Company

Perrigo-logo

Headquarter: Michigan

Perrigo Companys background:

Perrigo-Company

Established in 2013, Perrigo Company is an American Irish-registered manufacturer. The company is committed to providing consumers with “high-quality and affordable care products” to make their lives better.

Perrigo invests heavily in research every year, and drives innovation through a combination of internal research and external collaborations. The brands Nicotinell and Nicaway under Perrigo Company are highly trusted by consumers.

Key Products:

ibuprofen

Ibuprofen

Ferrous-Gluconate-Tablets

Ferrous Gluconate Tablets

Recommend Reason

  • The company enhances personal well-being by authorizing consumers to proactively prevent or treat self managed illnesses.
  • The company has formulated the “Play to Win”strategy, which emphasizes putting the interests of patients and customers first and leading industry development through continuous innovation.
  • Perrigo has also made breakthroughs in the application of artificial intelligence technology, accelerating drug development and production processes through AI.

17.Theravance Biopharma

Theravance-Biopharma-logo

Headquarter: South San Francisco

Theravance Biopharma background:

Theravance-Biopharma

Theravance Biopharma is a diversified biopharmaceutical company with the core goal of creating drugs that help improve the lives of patients with serious illnesses. The company has conducted the first patient medication in a registered phase III study evaluating ampreloxetine (TD-9855) for the treatment of symptomatic neurogenic orthostatic hypotension (nOH).

The core purpose of the company is to create drugs that can change people’s lives. The company has utilized decades of expertise to develop FDA approved YUPELRI (reverenacin) inhalation solution for maintenance therapy in patients with chronic obstructive pulmonary disease.

Key Products:

yupelri

YUPELRI

Recommend Reason

  • Theravance Biopharma has gradually developed into one of the giants in the global pharmaceutical industry through mergers and acquisitions, R&D innovation, and globalization strategies.
  • The company has also demonstrated its foresight in innovative research and development by collaborating with external institutions.

18.Incyte Corporation

Incyte-Corporation-logo

Headquarter: Delaware

Incyte Corporations background:

Incyte-Corporation

Incyte Corporation is a biopharmaceutical company founded in 1991, headquartered in Wilmington, Delaware, USA. The company’s business covers the United States, Canada, Europe, and Japan.

To positively impact patients’ lives and provide new solutions, drug discovery and development work is led by a group of immunology, chemistry, and biologists. Incyte Corporation is a pharmaceutical company focusing on AIDS, cancer, and inflammatory diseases. It also develops clinical business in its European headquarters in Morge and its Tokyo office in Japan.

Key Products:

Opzelura

Opzelura

Zynyz

Zynyz

Recommend Reason

  • Incyte Corporation’s products are all approved by the FDA.
  • The company’s antibiotic products are sold to multiple countries in Europe, Asia, and other regions.
  • After years of development, the company has continuously researched and developed new products, which are highly favored by consumers.

Headquarter: Pennsylvania

Venatorxs background:

Venatorx focuses on discovering and developing novel anti infective drugs for the treatment of multidrug-resistant bacterial infections and difficult to treat viral infections. Venatorx is a world-class internal research and development institution that has applied for over 100 patents and is involved in multiple research projects.

Its main product Cefepime is a widely used beta lactam antibiotic that can combat sensitive Gram negative and Gram positive bacteria.

Key Products:

Cephalexin-Hydrate

Cephalexin Hydrate

Recommend Reason

  • Venatorx is a world-class internal research and development institution that has applied for over 100 patents and is involved in multiple research projects
  • Venatorx focuses on multidrug-resistant bacterial infections and difficult to treat viral infections.
  • The company’s antibiotic products are all approved by the FDA.

20.Acurx Pharmaceuticals

Acurx-Pharmaceuticals-logo

Headquarter: New Jersey

Acurx Pharmaceuticalss background:

Acurx-Pharmaceuticals

Founded in 2017, Acurx Pharmaceuticals is a biopharmaceutical company primarily responsible for the research and development of antibiotics.

Acurx’s approach is to develop candidate antibiotics that block the novel target DNA polymerase IIIC (Pol IIIC), inhibit DNA replication, and lead to cell death in Gram positive bacteria.

Key Products:

Trogarzo

Trogarzo

Recommend Reason

  • Acurx Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to developing novel antibiotics
  • The company focuses on developing new antibiotics and has obtained multiple certifications, including patents in the United States, Israel, and Japan.
  • All products of the company have undergone third-party testing and certification.

Conclusion

Antibiotics are a class of drugs that can inhibit or kill the growth and reproduction of other microorganisms, widely used to treat various infections caused by bacteria. Different antibiotics can treat various diseases, and there are many antibiotic manufacturers in the United States. Do you know the top 20 antibiotic manufacturers in the USA? If you have any further questions, please feel free to contact AIPAK Engineering at any time.

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